| 저자 |
Heo Jung Yoon* 1, Won Hee Nam1, Seok Hui Kang1, Gyeongmin Jeong1, Kyu Hyang Cho1, Jong Won Park1, Kyung Woo Yoon1, Jun Young Do1 |
| 초록 |
Background: There were few data regarding whether cystic fluid in autosomal dominant polycystic kidney disease (ADPKD) is associated with body composition measurement using bioimpedance analysis. The aim of the present study was to evaluate the difference between bioimepdance analysis and dual-energy X-ray absorptiometry in peritoneal dialysis patients with or without autosomal dominant polycystic kidney disease.
Methods: We reviewed the medical records at Yeungnam University Hospital in Korea to identify all adults who received peritoneal dialysis between January 2001 and August 2014. The patients included the study had undergone body composition measurement. Matched for age, sex, body mass index, residual renal function, 11 patients with ADPKD and 11 patients without ADPKD were included. We identified 11 ADPKD patients who had body composition measurements performed by both techniques in one or more instances, totally 26 pairs of measurements and 11 non-ADPKD patients who had body composition measurements performed by both techniques in one or more instances, totally 27 pairs of measurements.
Results: The mean follow-up period was 51.4 ± 12.8 years in ADPKD group and was 51.4 ± 12.8 years in non-ADPKD group. There were no significant differences in sex, body mass index, and residual renal function between the two groups. Biases for total fat mass were in -0.43 kg (95% CI, -1.36 kg to 0.48 kg) in ADPKD group and -1.68 kg (95% CI, -2.57 kg to -0.79 kg) in non-ADPKD group. Those for total fat mass were 3.32 kg (95% CI, 1.46 kg to 5.19 kg) in ADPKD group and 4.14 kg (95% CI, 2.49 kg to 5.80 kg) in non-ADPKD group. Those for total bone mineral content were -0.86 kg (95% CI, -1.09 kg to -0.63 kg) in ADPKD group and -0.77 kg (95% CI, -0.96 kg to -0.58 kg) in non-ADPKD group.
Conclusion: There were no significant differences in body compositions between the two groups. Bioimpedance analysis may be applicable to measure body composition in peritoneal dialysis patients with ADPKD. |