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논문분류	춘계학술대회 초록집
제목	EPICARDIAL ADIPOSE TISSUE THICKNESS AS A PREDICTOR OF CORONARY ARTHEROSCLEROSIS IN HEMODIALYSIS PATIENTS
저자	Jiwon Ryu* 1, Kyung Min Kwak1, Myung Jin Choi1, Jong Woo Yoon1, Yong-Ki Lee2, Jung Woo Noh2, Jieun Oh2
출판정보	2016; 2016(1):
키워드	coronary atherosclerosis, epicardial adipose tissue, Hemodialysis
초록	Background: Excessive perivascular adipose tissue (PAT) may influence on inflammation of vessel so that stimulate atheroscleroticplaque formation of adjacent arteries. Epicardial adipose tissue (EAT) is the adipose tissue around the heart reaching from the myocardium to the pericardium and has no anatomical connection with coronary PAT. There have been several studies that increased EAT is independently associated with coronary heart disease and major adverse cardiovascular events similar to coronary PAT in general population. However, there are almost no studies about EAT on cardiovascular disease (CVD)in hemodialysis patients. Methods: Echocardiography was studied for EAT measurement in 27 hemodialysis patients. EAT was measured as highest adipose tissue thickness on the free wall of the right ventricle in parasternal long and short axis view. We investigated retrospectively the history and risk factors of CVD. Results: The mean age of 27 patients was 62.3 ± 8.88 years old and male were 74.1%. The causes of renal disease were diabetes (63.2%), hypertension (25.9%), polycystic kidney disease (7.4%) and unknown (3.7%). The mean EAT thickness was 4.35 ± 2.76 mm. CVD occurred in 17 patients (63.0%). In univariate analysis, the association between EAT thickness and CVD is significant (p = 0.028; 95% confidence interval (CI), 0.284-4.483). With multivariate analysis, EAT thickness has association to CVDindependently in compare to age, sex, cause of renal failure and smoking (p = 0.42; 95% CI, 0.322-0.979) Conclusion: In hemodialysis patients, it is important to predict CVD. EAT thickness could be useful as a marker which suspect CVD in patient without definite finding of CVD in echocardiography. With prospective study on large population, the predictable value of EAT thickness for CVD should be confirmed.
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