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논문분류	춘계학술대회 초록집
제목	Effect of Pre-transplant Dialysis Modality and Duration on Recipient's Outcome: A National Population-based Cohort Study between 2005 and 2008 in Korea
저자	Jung Nam An* 1, Yunmi Kim2, Eunjeong Kang2, Dong-Ryeol Ryu3, Kyoung Hoon Kim4, Yun Kyu Oh5, Chun Soo Lim5, Yon Su Kim2, Jung Pyo Lee5
출판정보	2016; 2016(1):
키워드	Dialysis, Kidney Transplantation, Mortality
초록	Background: So far the effects of pre-transplant dialysis modality or duration on clinical outcomes after kidney transplantation (KT) have not been investigated. Methods: We analyzed the clinical outcomes of 1,563 KT recipients among the 35,422 adult patients who were started hemodialysis and peritoneal dialysis from 2005 to 2008, using the Korean Health Insurance Review & Assessment Service database. Results: During the median 6.9 years follow-up after KT, 106 (6.8%) patients were died and 28 (1.8%) patients had experienced major adverse cardiovascular events (MACE). In the multivariable-adjusted Cox proportional hazard model, pre-transplant dialysis modality was not associated with an increased risk of mortality and the development of MACE. Pre-transplant dialysis duration was not associated with the occurrence of MACE; however, the HR for mortality (comparing the group greater than 10.8 months with the group lower than 10.6 months regarding the duration of dialysis before KT) was 1.66 (95% CI 1.11-2.47) in total populations. In each group of hemodialysis and peritoneal dialysis, the duration of pre-transplant dialysis was also an independent risk factor for mortality. Conclusion: The duration of dialysis before KT was independently associated with mortality, regardless of the dialysis modality in this national population-based cohort study. Pre-transplant dialysis duration could be useful marker in predicting mortality in KT recipients.
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