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논문분류	춘계학술대회 초록집
제목	Impact of acute kidney injury in elderly deceased donor on the post-transplant clinical outcomes: Multicenter cohort study
저자	Jeong Ho Kim1, Jong Hoon Lee2, Young Soo Kim3, Seungyeup Han4, Yu Ah Hong1, Yoon Kyung Chang1, Suk Young Kim1, Chul Woo Yang2, Woo Yeong Park4, Byung Ha Chung2
출판정보	2018; 2018(1):
키워드	Expanded criteria donor \| Acute kidney injury \| Deceased donor \| Kidney transplantation
초록	Objectives: The aim of this study was to investigate the impact of acute kidney injury (AKI) in elderly deceased donor (DDs) on post-transplant clinical outcomes. Methods: Five-hundred nine kidney transplant recipients (KTRs) receiving kidneys from 386 DDs were included from three transplant centers. KTRs were classified into the elderly-DD kidney transplantation (KT) or young-DDKT group according to the age of corresponding DDs and both groups were divided into the AKI-KT or non-AKI-KT subgroups according to the presence of AKI in DDs. We compared the clinical outcomes among those four groups and investigated the interaction between AKI in donors and donor age on the clinical outcomes. Results: The incidence of delayed allograft function was higher when the donors had AKI within elderly-KT and young-KT groups. In allograft biopsies within 3 months, chronic change was more significant in the AKI-elderly-KT subgroup than in the non-AKI-elderly-KT subgroup, but it did not differ between AKI-young-KT and non-AKI-elderly-KT group. AKI-elderly-KT showed higher risk for death-censored allograft failure than the other three groups and a significant interaction was observed between AKI in donors and old age on the allograft failure. Conclusions: In conclusion, the presence of AKI in elderly DDs significantly impacted the long-term allograft outcomes of KTRs, but it did not in young DDs.
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