대한신장학회

Skip Navigation: Skip to contents

KOR
ENG
전체메뉴보기

간행물 검색

현재 페이지 경로

HOME
간행물
간행물 검색

논문분류	춘계학술대회 초록집
제목	Idiopathic Systemic Capillary leak syndrome – A Case Report
저자	Jin Ho Hwang, Jung-ho Shin, Su-Hyun Kim
출판정보	2018; 2018(1):
키워드	capillary leak syndrome \| shock \| hemoconcentration \| hypoalbuminemia \| acute kidney injury
초록	Case Study: Idiopathis systemic capillary leak syndrome (ISCLS) is a rare disease characterized by recurrent episodes of acute life-threatening attacks of shock, hemoconcentration, and hypoalbuminemia. Increase of capillary permeability results in reversible plasma extravasation and subsequent vascular collapse accompanied by related symptoms. Here, we report a case of well controlling ISCLS, which can be difficult to meet in clinical field. A 47-year-old man was admitted to our institution with general weakness and abdominal pain on the day of admission. The patient had no underlying diseases or medications. He was never-smoker, and social drinker. The initial vital sign was stable, but the blood pressure (BP) decreased to 74/60 mmHg at 3 hours in the emergency room. Initial laboratory tests revealed several abnormal findings, including an elevated leukocyte count (29,180 cells/mm3), hemoglobin (Hgb, 22.6 g/dL), and hematocrit (66.1%), hypoalbuminemia (2.6 g/dL), and acute kidney injury (blood urea nitrogen [BUN] 28 mg/dL, Creatinine [Cr] 1.95 mg/dL). In bone marrow biopsy performed on polycythemia, reactive marrow was suspected without any abnormal findings. After treatment with vigorous fluid therapy and empirical antibiotics, he was recovered and discharged with Hgb 14.1 g/dL and BUN/Cr 13/0.96 mg/dL. There was a gradual upward trend in Hgb from 14.1 g/dL to 16.6 g/dL for 3 months after discharge, but there was no significant symptoms. However, he visited our hospital again on the 3 months and 2 weeks after the discharge with symptoms similar to the first episode. The BP was 70/50 mmHg, WBC 30,150 cells/mm3, Hb 19.7 g/dL, hematocrit 59.3%, BUN/Cr 39/2.93 mg/dL and albumin 3.0 g/dL, respectively. Based on these repeated clinical features, he was diagnosed with ISCLS. Based on the case series reported previously, bambuterol 10 mg and theophylline 400 mg once-a-day were prescribed, he has been following by 8 months without recurrence.
원문(PDF)	PDF 원문보기

목록

위로가기