대한신장학회

Skip Navigation: Skip to contents

KOR
ENG
전체메뉴보기

간행물 검색

현재 페이지 경로

HOME
간행물
간행물 검색

논문분류	춘계학술대회 초록집
제목	Low phase angle predicts anemia in hemodialysis patients
저자	Jong Hyun Jhee1, Kyoung Sook Park2, Tae-Ik Chang2, Sug Kyun Shin2, Ea Wha Kang2
출판정보	2018; 2018(1):
키워드	phase angle \| anemia \| bioelectrical impedance \| hemoglobin \| hemodialysis
초록	Objectives: Phase-angle (PA) measured by bioelectrical impedance analysis (BIA) is an index of cellular health and function. It is also associated with malnutrition-inflammation and survival in dialysis patients. Anemia in these population is common and associated with chronic inflammation. We aimed to investigate whether PA is associated with anemia in maintaining HD patients. Methods: In this prospective observational study, a total of 102 incident patients who started HD from 2000 to 2018 were enrolled. PA was measured at 50 kHz using multifrequency BIA (Inbody S10, Biospace, Seoul, Korea). Patients were divided into two groups according to sex-specific levels of PA (low vs. high; male > 5.0 and female >4.6). The mean levels of monthly checked hemoglobin were used for 3 months. Results: The mean age was 63.3 ± 12.1 years and 58 (56.9%) patients were male. PA levels were positively associated with mean hemoglobin levels (coefficient, 0.20; P = 0.04), whereas negatively associated with the dose of darbepoetin-alfa (coefficient, -0.32; P = 0.01). In multivariate linear regression analysis, higher phase angle was significantly associated with higher levels of hemoglobin (β, 0.20; 95% confidence interval, 0.02-0.39; P = 0.03) after adjustment for age, sex, extracelluar fluid status, histories of hypertension, diabetes and cardiovascular events, use of darbepoetin-alfa, serum albumin, low density lipoprotein cholesterol, high-sensitivity C reactive protein, and serum iron. This results were similar in sex-specific PA groups that high PA group was associated with higher mean hemoglobin levels (β, 0.45; 95% confidence interval, 0.01-0.89). Conclusions: This study suggests that measurement of PA via BIA could be helpful for predicting anemia status in maintaining HD patients.
원문(PDF)	PDF 원문보기

목록

위로가기