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논문분류	춘계학술대회 초록집
제목	Impact of liver cirrhosis on the outcomes of peritoneal dialysis
저자	Younglee Jung1, Jae Yoon Park2, Chung Sik Lee3, Hyunjin Ryu1, Yaerim Kim1, Dong Ki Kim1, Chun-Soo Lim1, Yon Su Kim1, Kook-Hwan Oh1, Seung Seok Han1
출판정보	2018; 2018(1):
키워드	peritoneal dialysis \| Liver cirrhosis \| technical failure
초록	Objectives: Peritoneal dialysis (PD) has become an increasingly popular treatment modality for end-stage renal disease. However, its application to the patients with liver cirrhosis (LC) and subsequent outcomes have not been thoroughly evaluated. Methods: A total of 1,366 patients (≥ 18 years old), who started PD at four tertiary referral centers between January 2000 and December 2015, were initially reviewed. When the presence of LC was confirmed by radiologic evaluations, 45 patients with LC were finally analyzed (LC-PD). Using multivariate Cox hazard ratio (HR) model, their outcomes such as technical failure, infection, and mortality were compared with non-LC patients receiving PD (non-LC PD) or LC patients receiving hemodialysis (LC-HD), all of whom were selected by 1:1 matching on age, gender, catheter insertion date, and diabetes mellitus. Results: During the mean follow-up duration of 43 ± 35.8 months, 17 LC-PD encountered technical failures, and this rate was higher than that of non-LC-PD with HR of 3.0 (1.03–8.90). When evaluating infection episodes, the most common causes for peritonitis and exit site infection were Escherichia coli (5.8%) and Staphylococcus aureus (19.3%), respectively; these event rates of LC-PD were not different from those of non-LC-PD. All-cause mortality rates were similar between LC-PD and non-LC-PD groups, but the LD-PD group had a lower HR of mortality [0.2 (0.04–0.94)] than the LC-HD group. Conclusions: Although infectious and survival outcomes of PD are not altered by the presence of LC, it may raise the technical problems of PD maintenance. Figure 1. Technical failure-free survival curves between LC and non-LC patients.
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