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논문분류	춘계학술대회 초록집
제목	Risk factors of proteinuria by ordinal logistic regression; Korean National Screening Data
저자	Yu-Mi Yang1, Soon Kil Kwon1, Hye-Young Kim1, Sun Moon Kim1, Hyunjeong Cho1, Tae-Young Heo2
출판정보	2018; 2018(1):
키워드	proteinuria \| metabolic syndrome \| hypertension \| obesity
초록	Objectives: Routine dipstick screening for proteinuria is biennially provided to all Korean population. Proteinuria is an independent risk factor of renal disease progression and also could be an important marker of atherosclerosis and vascular inflammation. However, there is still lack of data about the association between proteinuria and other cardiovascular and renal risk factors in the general population. We investigated parameters which used for routine metabolic disease screening to whom showed incidental proteinuria. Methods: We used data of National Health Insurance Screening Data in 2015 of 1,000,000 random individuals. Compared proteinuria with screening markers such as weight, waist circumference, blood pressure, lipid, creatinine, smoking and drinking. All data were analyzed by ordinal logistic regression. Results: Total 93,654 individuals were enrolled, and 89,509 (95.6%) were negative for proteinuria. 2,194 (2.3%) were trace and 1,951 (2.1%) were 1+ of dipstick proteinuria. There was significant association between proteinuria (-, trace, +) and waist circumference (80.8±9.6 vs. 80.9±105 vs 83.3±11.4 cm; p < 0.001), fasting glucose (97.3±21.4 vs. 100.6±28.1 vs. 113.3±45.0; p < 0.001), triglyceride (128.4±92.3 vs. 129.9±96.9 vs. 153.2±119.0; p < 0.001), and gamma GT (37.4±46.3 vs. 41.7±56.0 vs. 51.5±74.1; p < 0.001) as metabolic syndrome markers. Also, there was significant association proteinuria and systolic blood pressure (120.6±13.7 vs. 121.0±15.7 vs. 125.6±16.7; p < 0.001), diastolic blood pressure (75.4±9.6 vs. 75.7±10.7 vs. 77.9±11.4; p < 0.001), and serum creatinine (0.88±0.36 vs. 0.88±0.23 vs. 1.04±0.72; p < 0.001) as cardio and renal markers. Conclusions: Proteinuria on routine screening of healthy individuals also could be an important indicator for metabolic and vascular disease.
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