대한신장학회

간행물 검색

현재 페이지 경로

논문분류	춘계학술대회 초록집
제목	Metabolomics based biomarkers as clinical outcome indicator in Minimal change diseases
저자	Young Wook Choi1, Jung Nam An1, Jin Seoung Hyeon5, Jin Hyuk Kim1, Seung Hee Yang4, Sang-Ho Lee2, Jang-Hee Cho3, Dong Ki Kim4, Geum-Sook Hwang5, Jung Pyo Lee1
출판정보	2018; 2018(1):
키워드	Urine metabolomics \| Biomarker \| MCD
초록	Objectives: Minimal change disease (MCD) is well known as one of the glomerulonephritis (GN) that recur frequently. We investigated the clinical outcome of Metabolomics based biomarkers in patients with MCD. Methods: Urine samples from healthy control (n=61), primary MCD (n=81) and MCD follow up (n=35) were analyzed with NMR-spectroscopy. Metabolites were then quantified and compared between groups. Results: In the urine samples, metabolites that showed a clear difference between the healthy control group and the MCD group were analyzed. In addition, when these metabolites level were completely remission in the MCD follow up group, they were restored to the healthy control group level. Conclusions: In this study, we suggest that metabolites biomarker is a reliable tool for the prediction of MCD prognosis and guidance of therapeutic plans.
원문(PDF)	PDF 원문보기

간행물 검색