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논문분류	춘계학술대회 초록집
제목	Prevalence and Clinical Characteristics of Saudi Dialysis Patients with or without Positive Family Histories of Kidney Disease.
저자	Abdulla Al-Sayyari, Dujana Mousa, Abdulkareemm Alsuwaida, Fayez Hejaili
출판정보	2019; 2019(1):
키워드	Family history \| CKD
초록	To evaluate the prevalence and clinical characteristics of Saudi dialysis patients with a positive family history of kidney disease and to compare these to those without such a history. Secondary objective was to assess the certainty of the diagnoses of causes CKD among by the physicians This is a cross-sectional survey based study on adult Saudi patients on hemodialysis in in four Saudi cities. The survey had two parts. The first part (filled by the physicians) asked about the patient’s sex, age, dialysis vintage, CKD vintage, cause of the renal failure and whether the diagnosis is definitive or speculative. The second part (filled by the patients) asked about the presence of kidney disease among first degree relatives 1080 patients were included, 55.4% males. The mean age was 56.1±20 years, the dialysis vintage was 5.7±5.9 years and the mean time between diagnosis of CKD and onset of dialysis was 3.0±5.6 years Table 1 shows the causes of the CKD as determined by the patients’ physician and its certainty; 57.8% were either “unknown” (33%) or only “speculative (25.3%). In those with a diagnostic label, the diagnosis was thought to be definitive in only 62.2% of the cases’”. 21.5% had first-degree relatives with kidney disease. More patients with “unknown” or “hypertensive” diagnosis were seen among patients with FH than in those without (p=007 and 0.005). No difference in the prevalence FH was seen by age (p=0.5). Dialysis vintage was shorter (p=0.03) and CKD vintage longer (p=0.0001) in the patients with FH (table 2) More patients with “unknown” or “hypertensive” diagnostic labels were seen in patients with FH suggesting that under the umbrella of “unknown” or “hypertensive” diagnostic labels, genetically-based kidney diseases might well be concealed. Dialysis vintage was significantly shorter and CKD vintage AM24was significantly longer in the patients with FH.
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