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논문분류 춘계학술대회 초록집
제목 Impact of Donor and Recipients Factors on Patient and Graft Survival among Recipients of Deceased Kidney Transplants at KAMC
저자 Abdulla Al-Sayyari, Shahad Al Onazi
출판정보 2019; 2019(1):
키워드 Transplanantation | Deceased donor
초록 To investigate the patient and graft survival among recipients of deceased kidney transplants   All the deceased kidney transplants between January 2004 and December 2015 were included. Data  on donors and recipients were collected    The patient and graft survival and impact of  donor and recipient’s characteristics were analyzed      207 transplants were carried out; mean age   of the donors and recipients were 37.1±11.8 yrs. and 37.7±17.4 yrs. respectively. The prevalence of male gender amongst the donors and recipients was 90.8 % and 58.7% respectively   The median graft and patient survival were 7.5 ±3.4 and 7.95±3.2 years respectively. The graft survival at one and five years was 95% and 73.8% respectively The graft survival was not affected by the donor or recipient sex.  However, the median graft survival was longer when no graft biopsy was (8.2 versus 6.9 years (p=0.027) and when the biopsy diagnosis of CNI nephrotoxicity compared to  ATN or AMR  (8.19. 6.35 and 3.66 years respectively)  (p= 0.0047) The median graft survival was significantly longer in recipients of kidneys from donors who died as result of trauma than  from CVA ( 5.9 and 5.3 years respectively (p= 0.029) (fig 1_ The median graft survival in recipients for donors who developed AKI during their ICU stay  was shorter  ( 6.97 and 8.16 years respectively, p=0.0062) (fig 2) The  median graft survival in recipients   was l younger  for younger donors The mean, mean BP at harvesting of the kidneys did not affect the graft survival The actuarial graft survival at one and five years was 95% and 73.8% respectively. The graft survival was affected by the donor’s age, whether a graft biopsy was done, cause of brain death and development of AKI in the donor, but not by donor’s or recipient’s sex, posttransplant DM or hypertension or  donor’s BP at harvesting
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