| 논문분류 | 춘계학술대회 초록집 |
|---|---|
| 제목 | Obstructive sleep apnea as a risk factor for incident end-stage renal disease: A Nationwide Population-based Cohort Study from Korea |
| 저자 | Hong Sang Choi, Jeong Ho Lee, Minah Kim, Tae Ryom Oh, Chang Seong Kim, Eun Hui Bae, Seong Kwon Ma, Soo Wan Kim |
| 출판정보 | 2019; 2019(1): |
| 키워드 | Obstructive sleep apnea | End-stage renal disease | National Health Insurance |
| 초록 | Obstructive sleep apnea (OSA) is known to be associated with metabolic dysregulation and incident cardiovascular diseases. However, its association with end-stage renal disease (ESRD) has not been clarified. This study aimed to evaluate longitudinally whether OSA is an independent risk factor for ESRD. This retrospective nationwide population-based cohort study included data on 93,051 patients with OSA and 465,255 age- and sex-matched controls without OSA obtained from the Korean National Health Insurance Service database from 2009 to 2014. A Cox proportional-hazards model with multivariable adjustment was used to evaluate the association between OSA and incident ESRD. A significantly higher incident ESRD rate (odds ratio 1.274, 95% confidence interval 1.018-1.583) was observed for patients with OSA than for matched controls. The OSA group remained predictive of higher risk of ESRD incidence in subgroups of age ≥65 years, hypertension, dyslipidemia and chronic kidney disease (CKD). OSA was an independent predictor of incident ESRD. |
| 원문(PDF) | PDF 원문보기 |