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논문분류	춘계학술대회 초록집
제목	Vascular Catheter-Site Care Using Different Skin Antiseptics for Prevention of Catheter-Related Blood Stream Infection: A Meta-Analysis
저자	Martin Ogbac, Euodia Guinmapang, Frederick Ogbac
출판정보	2019; 2019(1):
키워드	Vascular access \| Infection \| Catheter \| Antiseptic \| Bloodstream Infection
초록	Infections are common complications among end-stage kidney disease (ESRD) patients undergoing hemodialysis (HD). It is the second most common cause of death and a major cause of hospital admission among ESRD patients. Among the different infections that ESRD patients are at risk, catheter-related blood stream infection (CRBSI) plays a significant role. Several guidelines have proposed measures to prevent CRBSI including different topical solutions to disinfect the access site. The 2 most commonly used solutions are chlorhexidine and povidone-iodine. This study aims to identify which among the 2 most commonly used disinfectants is more effective in preventive CRBSI. Several published randomized controlled trials about the different topical solutions in preventing catheter-related bloodstream infection were identified using MEDLINE, COCHRANE, and EMBASE. The studies included were published from 1990 to 2018. The primary outcome was the incidence of catheter colonization and CRBSI. 8 studies were included in this analysis. A total of 4902 central vascular insertions were identified. Patients, who were enrolled in the chlorhexidine group had a catheter bacterial colonization incidence of 5.17% while those in the povidone-iodine group had 7.9%. Patients in the chlorhexidine group had a CRBSI incidence of 2.9% while those in the povidone-iodine group had 4.6%. The use of chlorhexidine is more superior in preventing catheter colonization of central vascular catheters compared to povidone-iodine. It is not clear, however, whether which intervention is more effective in preventing catheter-related bloodstream infection as both groups demonstrated almost similar incidence of CRBSI.
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