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논문분류	춘계학술대회 초록집
제목	Studies on the effect of vitamin C on crystallization and crystal growth inhibition and dissolution of struvite crystals – an in vitro study
저자	Surya Ram Duwal, Muhammed Manzoor A.P., Rekha P.D
출판정보	2019; 2019(1):
키워드	struvite crystal \| ATRFTIR \| XRD \| FESEM
초록	-Effect on the of vitamin C on crystallization and crystal growth inhibition -Dissolution of struvite stone In this in vitro study the inhibitory effect of vitamin C in artificial urine was investigated against formation of struvite crystals. Struvite crystallization intensity was determined using single gel growth techniques. The crystals grown in presence of vitamin C and control were characterized by Attenuated Total Reflectance Fourier Transform Infrared Spectroscopy (ATR-FT-IR), X-ray powder Diffraction (XRD) and Field Emission Scanning Electron Microscope (FESEM). In addition, using an in vitro model, dissolution of struvite crystal in synthetic urine in the presence of vitamin C was also evaluated. Decreased in the number,weight, dimension, growth rate, depth of growth of struvite crystals and dissolved rapidly with the increasing concentrations of vitamin C was observed. As monitored by light microscopy, presence of vitamin C in the media slowed the crystal growth and the crystals assumed an octahedral crystal habit. ATR- FT-IR spectra of struvite crystals revealed the presence of characteristic functional groups. Powder XRD study also confirmed the structural similarity of the crystals grown in vitro. Crystals grown in the presence of vitamin C were pitted on their surface as shown by FESEM. Vitamin C can modulate the formation of struvite crystals and can hence be explored in to their potential application in the inhibition of struvite stone formation.
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