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논문분류	춘계학술대회 초록집
제목	Hypoalbuminemia is related with worse kidney outcomes and mortality after coronary artery bypass graft surgery
저자	Yeonhee Lee, Sejoong Kim, Dong Ki Kim, Kwon Wook Joo, Yon Su Kim, Chun Soo Lim, Ki Young Na, Seung Seok Han
출판정보	2019; 2019(1):
키워드	acute kidney injury \| albumin \| end-stage renal disease \| coronary artery bypass grafting \| mortality
초록	Hypoalbuminemia reflects several pathologic conditions such as nutritional deficiency and chronic inflammation. However, its relationships with kidney outcomes and a long-term mortality after coronary artery bypass grafting (CABG) remain unresolved. A total of 3,040 patients who underwent CABG at three tertiary referral hospitals between 2003 and 2015 were retrospectively reviewed. Patients were categorized by quartiles of preoperative albumin levels. Odds ratio (OR) for postoperative acute kidney injury (AKI) and hazard ratio (HR) for end-stage renal disease (ESRD) and all-cause mortality were calculated after adjustment of multiple covariates. Mean preoperative albumin level was 3.8 ± 0.6 g/dL. The prevalence of postoperative AKI was 34.4%, 30.1%, 24.4%, and 19.8% from 1st to 4th quartiles, respectively. The 1st quartile had higher risks of AKI (adjusted OR, 1.4 [1.04–2.00]) and ESRD (adjusted HR, 3.1 [1.02–9.31]) than the 4th quartile. During the mean follow-up period of 6 years (maximum 13 years), 854 patients (25.9%) died. The 1st quartile had a higher risk of mortality than the 4th quartile with an adjusted HR of (1.7 [1.23–2.20]). Because hypoalbuminemia is associated with AKI, ESRD, and all-cause mortality, serum albumin levels should be monitored during the perioperative period of CABG.
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