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논문분류	춘계학술대회 초록집
제목	Pattern of infections in renal transplant recipients : A perspective from a rural population of South India
저자	Srinivas Vinayak Shenoy, Ravindra Prabhu, Shankar Prasad, Dharshan Rangaswamy, Indu Rao
출판정보	2019; 2019(1):
키워드	Infections \| Renal Transplant \| Mortality \| Rural Population
초록	Infections are ranked as the second most common cause for mortality after renal transplant and lead to poorer quality of life and increase in healthcare spending . India , especially the rural population presents challenges - poverty , lack of access to healthcare , poor general hygiene which may influence outcomes . The objective of this study is to 1. Study pattern of infections in renal allograft recipients, their incidence, risk factors and the influence on allograft function Study setting : A tertiary care centre in South India providing healthcare services to a predominantly rural population Type of study : Retrospective , Observational Study Period : January 2018 to January 2019 Sample Size : 64 Renal allograft recipients Immunosuppression : Induction – Basiliximab /Antithymocyte Globulin (ATG) (at 1.5mg/kg)/No Induction Maintainence : Tacrolimus (0.1mg/kg) + Mycophenolate Mofetil (2grams/day) + Prednisolone ( 20mg/day) 64 patients with a mean follow up of 34.2 months (see attached tables/figures) had a total of 75 infection episodes . Urinary tract infections were the most common (32%) . Onset of 1st infection was early (median – 3months) . More than half ( 59.3%) patients had atleast 1 infection episode during the follow up period . 66.7 % of the cause for mortality during the follow up period was attributable to infection Cadaveric transplants recipients were associated with higher percentage of infections(72.2% versus 51%) but not statistically significant (p=0.78) . There was no difference in the incidence of infections between different induction regimes (p=0.96) Infections in this cohort of rural Indian population occurred in more than half of the patients , occurring early in the post transplant period Infections maybe the most common cause for the death in the initial few years of follow up of the transplant recipients necessitating the importance of early recognition and prompt treatment.
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