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논문분류 춘계학술대회 초록집
제목 Muscle Mass, Physical Activity and Chronic Kidney Disease in Older Adults
저자 Soo Jeong Choi, Gang Jee Ko, Min Sung Lee, Sujung Park, Byung chul You, Moo Yong Park, Jin Kuk Kim, Seung Duk Hwang
출판정보 2019; 2019(1):
키워드 Chronic kidney disease | sarcopenia | physical activity
초록 Sarcopenia can affect the prognosis of patients with chronic kidney disease (CKD). Exercise and nutritional therapy are carried out to prevent processing sarcopenia. CKD and sarcopenia increase in aging process. However, there are only few reports on physical activity and CKD stage in older people and their association with sarcopenia. The aim of this study is to examine the association between CKD and physical activity in older adults. This cross-sectional study based on the Korean Fraility and Aging Cohort study represents a population of 3014 people aged 70 years or over. Anthropometric, physical performance measurements and baseline laboratory data were collected. CKD was defined by estimated glomerular filtration rate < 60ml/min/1.73m2. The mean age of the participants was 76.0±3.9 years old and females compromised 52.5%. The male and female CKD patients were 231 and 160 (16.1 vs 10.1 %, p<0.001). Appendicular skeletal muscle mass (ASM) was negative correlated with serum creatinine in males (ß=-0.414, 95% CI -0.811~-0.160, p=0.042), while ASM was not different with serum creatinine in females. Patients with slow speed gait increases according to CKD stage. While patients with less ASM and slow sit-to-stand time increased according to CKD stage in males, those were no different in female. Patients with slow up-to-go time increased according to CKD stage in females(table 1). ASM and physical activity except handgrip power were associated with CKD stage after adjusting sex, age, height, weight and diabetes. Low ASM and physical activity increase according to CKD stage in older people. But more detailed study about sex difference in CKD and sarcopenia is needed for older people.    
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