대한신장학회

Skip Navigation: Skip to contents

KOR
ENG
전체메뉴보기

간행물 검색

현재 페이지 경로

HOME
간행물
간행물 검색

논문분류	춘계학술대회 초록집
제목	Risk factors of hypercalcemia after kidney transplantation
저자	Han Ro, Yeon Ho Park, Jaeseok Yang, Curie Ahn
출판정보	2019; 2019(1):
키워드	hypercalcemia \| kidney transplantation
초록	Kidney transplantation (KT) is the best choice for patients with end-stage kidney disease (ESKD) because KT improves complications of ESKD and patient’s outcomes. However, complications of ESKD after kidney transplantation are not all solved, and one of them is hypercalcemia. The purpose of this study was to identify the risk factors of hypercalcemia after KT. One thousand eighty kidney transplant recipients was enrolled in multicenter observational cohort study (KNOW-KT) between July 2012 and August 2016. Nineteen patients with parathyroidectomy before KT excluded. Nine hundred forty-eight patients with calcium and albumin level at pretransplant and 1 year after KT were reviewed. Hypercalcemia was defined as albumin-corrected calcium ≥ 10.2 mg/dL. Serum corrected calcium level (mg/dL) at pre-transplant and 1 year after KT were 8.83 ± 0.88 and 9.22 ± 0.61, respectively (p<0.001). Parathyroid hormone (PTH) level (pg/mL) at pre-transplant and 1 year after KT were 275.2 ± 268.7 and 86.3 ± 66.5, respectively (p<0.001). Percentages of hypercalcemia at pre-transplant and 1 year after KT were 5.5 and 7.0, respectively(p<0.001). However, PTH level (pg/mL) at 1 year after KT between patients with and without hypercalcemia at 1 year after KT showed the significant difference (79.7 ± 73.4 vs. 195.1 ± 125.5 pg/mL; p<0.001). When divided into four groups using corrected calcium levels at pretransplant and 1 year, PTH levels (pg/mL) at pretransplant were 353.9 ± 269.7 in the persistent hypercalcemia group, 244.7 ± 504.9 in the improved hypercalcemia group, and 518.5 ± 350.6 in the developed hypercalcemia group. PTH levels (pg/mL) at 1 year were 242.2 ± 157.4 in the persistent hypercalcemia group, 75.2 ± 52.6 in the improved hypercalcemia group, and 176.3 ± 106.6 in the developed hypercalcemia group. Hypercalcemia and high parathyroid hormone level at pretransplant were risk factors of hypercalcemia at 1 year after KT.
원문(PDF)	PDF 원문보기

목록

위로가기