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논문분류	춘계학술대회 초록집
제목	Clinical Implication of Duration of Graft Function Recovery after Kidney Transplantation
저자	Jeong Ho Kim, Yu Ah Hong, Suk Young Kim, Yoon Kyung Chang
출판정보	2019; 2019(1):
키워드	Kidney transplantation \| Graft function recovery
초록	Acute kidney injury is frequently detected as slow recovery of graft function (SGF) or delayed recovery of graft function (DGF) after kidney transplantation (KT). It is known as a risk factor of poor long-term graft survival, but definitions of SGF or DGF are various. In this study, we investigated the clinical effect of duration of graft function recovery on KT. We retrospectively analyzed 150 kidney transplant recipients who took kidney from 127 living and 23 deceased donors (DDs). These cases were divided into four groups; the recovery of graft function within 3 days (Group A, n=54), 7 days (Group B, n=33), 14 days (Group C, n=22) after KT and the non-recovery of graft function within 14 days (Group D, n=41) according to allograft function assessed by the Modification of Diet in Renal Disease (MDRD) estimated glomerular filtration rate (60 mL/min/1.73 m2). We compared the clinical outcomes such as acute rejection, allograft, and patient survival across those groups. The mean total ischemic time was longer in group C, D than A, B groups insignificantly (122.7±158.7, 109.6±94.5 vs. 72.4±65.5, 80.4±81.0, p>0.05). The DDKT rate was significantly higher in group C, D than group A (22.7%, 23.3% vs. 7.4%, p<0.05). The incidence of acute rejection was significantly higher in group B, D than group A, C (59.4%, 43.9% vs. 22.2%, 22.7%, p<0.05). The long-term graft survival rate was significantly lower in group D than the other groups, but not different among A, B, and C groups. The patient survival rate did not differ among the four groups. Our study showed that the non-recovery of graft function within 14 days after KT might be associated with poor long-term allograft outcome.
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