| 초록 |
"PURPOSE OF THE STUDY:The Concept of “Organ Cross Talk”-Bidirectional interaction between kidney and other organs has led to the emergence of Newer Syndromes like Hepato-Renal, Cardio-Renal, Pulmonary Renal Syndrome etc…But the term “Cerebro-Renal Syndrome” coined by Kjellstrand in 1981,has not caught the attention of fellow nephrologists till now.This paper aims to revive interest in this TopicMATERIALS AND METHODSAcute Kidney Injury following Neurovascular syndrome, Traumatic-Brain Injury and Infections, during 2015 in a large Corporate Hospital were studied. The various special features were analyzed RESULTSTotal Cases 481 Male 384 79% Female 105 21% TYPE OF CASES Neurovascular Syndrome 217 Traumatic-Brain Injury 258 CNS infections 6 AGE NVS 20–60 yrs 58.4%TBI 20-40 yrs 33%(Young people more involved in Road accidents) CEREBRORENAL SYNDROME INCIDENCE Neurovascular Syndrome 86/217 39.6% Traumatic-Brain Injury 65/258 25% CNS infections 2/6 33% Total 153/481 31.6% AKI TYPE Mainly Pre-Renal Azotemia UREA: CREATININE RATIO > 40 NVS 80/92 à86.9% TBI 50/92 à76.9% INFECTIONS 65/2 à100%Normalisation of Values at 1month NVS 53/75 à70.6% TBI 55/65 à84.6% INFECTIONS 2/2 à100% CONCLUSIONS: • CRS frequently complicates major CNS events: 31.6%Our figures are higher than 25% and 17% reported by Elizabeth Moore,Australia 2010 and Minesh khatri,USA,2014CRS occurs in same frequency as CardioRenal Syndrome 24-45% HepatoRenal Syndrome20-40% • AKI was of Pre–Renal Azotemia type. Most cases returned to normal urea/creatinine at 1month-Showing the temporary and functional nature of this AKI, as is seen HepatoRenal SyndromeNone progressed to ATN needing Dialysis While every other Organ Failure enjoys a privileged name, AKI complicating majorCNSeventsissimplycalledAKI and it richlydeservesthe name Cerebro-Renal Syndrome as mooted by Kjellstrandin1981" |