대한신장학회

Skip Navigation: Skip to contents

KOR
ENG
전체메뉴보기

간행물 검색

현재 페이지 경로

HOME
간행물
간행물 검색

논문분류	춘계학술대회 초록집
제목	The protective beneficial role of Dandelion (Taraxacum) Methanolic Extract on Kidney Function in STZ-Induced Diabetic affected Rats: accouterments on Selected Metabolic Markers
저자	PRAGYA SHARMA
출판정보	2020; 2020(1):
키워드	Dandelion (Taraxacum) \| Kidney Function \| Metabolic Markers \| methanolic root \| metformin
초록	Present outcomes Dandelion (Taraxacum) possesses ant- hyperglycemic effects. The effects of Taraxacum on diabetic complications such as DN, however, have not been established. Accordingly, this study seeks to investigate the effects of Taraxacum on kidney function in STZ-induced diabetic rats. Methanolic extracts (ME) of Taraxacum root were used in this study. Short-term effects of Taraxacum methanolic extract on kidney function and MAP were studied in STZ-induced diabetic rats treated twice daily with Taraxacum methanolic root extract (250 mg/kg), insulin (175 μg/kg, s.c.), and metformin (500 mg/kg) for 5 weeks. Taraxacum methanolic root extract appreciably increased Na+ excretion outputs in STZ-induced diabetic rats by comparison to STZ-diabetic regulate rats. Taraxacum methanolic extract significantly increased GFR in STZ-diabetic rats with a concomitant decrease in creatinine concentration and also reduced kidney-to-body ratio, albumin excretion rate (AER), and albumin creatinine ratio (ACR). Taraxacum methanolic extract appreciably reduced MAP in STZ-diabetic rats by comparison with STZ-diabetic control rats. These results suggest that Taraxacum methanolic root extract not only lowers blood glucose but also has beneficial effects on blood pressure and renal function These observations propose that Taraxacum may have beneficial effects on some processes that are associated with renal derangement in STZ-induced diabetic rats.
원문(PDF)	PDF 원문보기

목록

위로가기