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논문분류	춘계학술대회 초록집
제목	External Validation of the Hennepin Transplant Risk Score for Prediction of Short-term Mortality and Morbidity after Deceased Kidney Transplantation
저자	Jisu Kim, Haesu Jeon, Myungyeon Kim, Arzu Velioğlu, Ye Na Kim, Ho Sik Shin, Yeonsoon Jung, Hark Rim, Anil Chandraker
출판정보	2020; 2020(1):
키워드	Hennepin Transplant Risk Score \| Deceased Kidney Transplantation
초록	In recent years, clinicians have been looking for objective scoring systems for providing accurate information on post-transplant outcomes. We tested the applicability of the Hennepin scoring system, which was recently validated in transplant recipients at the listing time in a different transplant center in the United States A total of 274 deceased kidney transplantation recipients (mean age 51.3∓14.9 years, F/M:113/161) transplanted between 2006-2015 were included in this study. In order to use the Hennepin score, age, functional status, cardiovascular co-morbidities, dialysis and diabetes status, were determined at the time of listing. A serious adverse outcome was defined as the presence of any of these events: mortality, graft loss, MI or stroke, ICU stay greater than 2 weeks, readmission requiring ICU admission, or care at a long-term care facility greater than 2 months (within the first year post transplant). Patients were stratified into 4 risk groups based on score (Table 1). Fifteen deaths and 19 graft losses were observed in the first year following transplantation. A total of 49 events occured in 43 patients. The incidence of severe adverse events 1 year post-transplant was 17.8 %. While only 8% of patients were stratified into the high risk group they accounted for 28% of the severe adverse outcomes, a patient in this group having a > 50% chance of a severe adverse outcome (Figure 1). The Hennepin transplant risk score showed moderately good discrimination for severe adverse events (c- statistics:0.648). These results provide external validation of the Hennepin score as a moderately good tool for discriminating short-term post-transplant morbidity for kidney transplantation recipients. The major advantage of this scoring is predicting the outcome at the listing time and providing a time for correction of pre-existing co-morbidities before transplantation.
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